Malignant Lymphomas of the Head and Neck:A Retrospective Study of 75 Patients

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A retrospective review of 75 patients of malignant lymphoma treated at the Department of Otolaryngology, Kurume University Hospital, during the 10 years from 1971 to 1980 was carried out. In this study, the determinate cases consist of previously untreated 61 patients with histological diagnosis of malignant lymphomas. The results were seen as follows; (1) A patient of Hodgkin's disease, mixed cellularity (MC) in CS III, nodal lesion, was a 26-year-old male. He is currently alive 45 months after the initial treatment with no evidence of relapsing lesion. (2) In 60 patients with non-Hodgkin's lymphomas, 1-, 2-, and 5-year cumulative survival rates calculated by the actuarial method were 65.5 %, 54.8 %, and 44.8 %, respectively. (3) In patients with non-Hodgkin's lymphomas in early stages or of the Waldeyer's ring, prognosis was better. (4) Patients in advanced stages presented lower survival rate. (5) Diffuse lymphoma, pleomorphic type showed the worst survival rate. (6) Among 31 deaths, 21 (68 %) were death from tumor dissemination, 5 (16%) from complication, 2 (6 %) from unknown cause, 3(10%) from intercurrent disease. (7) Pulmonary complications, particularly, pneumonitis was the most serious complication in non-Hodgkin's lymphomas. (8) Relapse rate was 44% in early stages. Relapse occurred most frequently within 1 year, but there were some late relapses. (9) Two patients with non-Hodgkin's lymphomas of the Waldeyer's ring had a gastrointestinal involvement at relapse. (10) Lastly, we propose diagnostic and therapeutic protocols for the patients with malignant lymphomas.
久留米大学医学部 The Kurume Medical Journal 編集部の論文

Malignant Lymphomas of the Head and Neck:A Retrospective Study of 75 Patients

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