Comparison of the anti-neuraminidase antibody responses to vaccination with influenza whole particle and hemagglutinin vaccines.
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概要
- 論文の詳細を見る
Two hundred eighty-two subjects were inoculated with influenza whole particle vaccines or hemagglutinin (HA) vaccines during the winter of 1978-1979. Antineuraminidase antibody (ANAb) responses to both vaccines were compared. Hemagglutinin-inhibiting antibody responses to the HA vaccines were as large as the responses to whole particle vaccines. ANAb responses to the whole particle vaccines were large for all strains in the vaccine. ANAb responses to the HA vaccines were not always large. Seroconversion (3×or more rise in ANAb titer) rates for A/USSR/92/77 one month after vaccination with HA vaccines varied from 32 to 40 % . They were as large as the rates after whole particle vaccines. The seroconversion rate for A/Yamanashi/2/77 was low (6 %) for the HA vaccine, although it was high (52 %) for the whole particle vaccine. The elevated ANAb titer after the vaccination with HA vaccines decreased to pre-vaccination levels earlier than with the whole particle vaccines.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Sato Yasumi
Department Of Gynecology And Obstetrics Senboku Kumiai Hospital
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HIROMATSU Yuji
Department of Endocrinology and Metabolism, Kurume University, School of Medicine
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Kaji Masaro
Department Of Bioclimatology And Medicine Adn Department Of Internal Medicine Research Institute Of
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Kobayashi Kenji
Departmant Of Zoology Graduate School Of Science Kyoto University
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ISHII KOZABU
Department of Internal Medicine, Kurume University School of Medicine
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KUROSAWA YOSHIRO
Department of Internal Medicine, Kurume University School of Medicine
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SHINGU TOSHIMITSU
Department of Pediatrics, Nichinan Prefectural Hospital
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INOKUCHI TETSUAKI
Department of Internal Medicine, Kurume University School of Medicine
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UMENO HIDEHARU
Department of Internal Medicine, Kurume University School of Medicine
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HAYASHIDA KAZUO
Oji Central Clinic, Nichinan
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MINAMINO TSUYOSHI
Omura Medical Association
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NAGAOKA MORIE
Omura Medical Association
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DEGUCHI MASATSUNE
Omura Medical Association
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MATSUO TAKASUKE
Omura Medical Association
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HONGO YOSHIRO
Omura Medical Association
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SHINGU TOSHIMITSU
Department of Pediatrics, Prefectual Nichinan Hospital
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SATO YASUMI
Department of Internal Medicine, Kurume University School of Medicine
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KOBAYASHI KENJI
Department of Internal Medicine, Kurume University School of Medicine
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