Inhibitory Effects of Platelet-rich Plasma on Osteoclast Differentiation in RAW264.7 Cells(International Symposium of Maxillofacial and Oral Regenerative Biology in Okayama 2005)
スポンサーリンク
概要
- 論文の詳細を見る
Platelet-rich plasma (PRP) is an autologous source of platelet-derived growth factors, and has been used successfully in oral surgery repair and in the placement of osseointegrated implants. However, little is known about the underlying release mechanisms of these factors or the manner in which inhibition of osteoclastic cells is regulated. The present study investigated the efficacy of PRP as an inhibitor of receptor activator of NF-kappaB ligand (RANKL)-induced TRAP-positive multinucleated cell formation in RAW264.7 cells. RANKL-induced formation of osteoclasts was significantly inhibited by treatment with PRP, while washed platelet treatment was more effective in inhibiting osteoclast formation. These results suggest that PRP and washed platelets are potent inhibitors of osteoclast differentiation.
- 硬組織再生生物学会の論文
著者
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Kobayashi Kenji
Department Of Cardio-renal Medicine And Hypertension Nagoya City University Graduate School Of Medic
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Kikuchi Hirotaka
Departments Of Endodontics Meikai University School Of Dentistry
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Nishikawa Hirofumi
Departments Of Endodontics Meikai University School Of Dentistry
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KATAYAMA Tadashi
Department of Agricultural Chemistry, University of Kyoto
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Duan Jianmin
Departments of Operative Dentistry, Meikai University School of Dentistry
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Suda Tomoyo
Departments of Endodontics, Meikai University School of Dentistry
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Satho Masashi
Departments of Endodontics, Meikai University School of Dentistry
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Sugi Yuki
Departments of Endodontics, Meikai University School of Dentistry
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Satho Masashi
Departments Of Endodontics Meikai University School Of Dentistry
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Sugi Yuki
Departments Of Endodontics Meikai University School Of Dentistry
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Suda Tomoyo
Departments Of Endodontics Meikai University School Of Dentistry
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Duan Jianmin
Departments Of Operative Dentistry Meikai University School Of Dentistry
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Katayama Tadashi
Department Of Agricultural Chemistry University Of Kyoto:(present Address)radiation Center Of Osaka
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Katayama Tadashi
Departments Of Operative Dentistry Meikai University School Of Dentistry
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Kobayashi Kenji
Departmant Of Zoology Graduate School Of Science Kyoto University
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Kobayashi Kenji
Departments Of Endodontics Meikai University School Of Dentistry
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