A Case of Chronic Hepatitis C with Sinus Bradycardia during IFN Therapy.
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概要
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The patient was a 55-year-old male with no history of heart diseases. He was administered recombinant IFN α-2b under the diagnosis of chronic hepatitis C. Since sinus Bradycardia (heart rate 40 bpm) appeared in the fourth week of administration (cumulative dose; 240 M.U), IFN was discontinued. Bradycardia was resolved 1 week after discontinuation of IFN and the treatment was resumed with a change of the regimen to IFN-β. Since no bradycardia was noted thereafter, IFN therapy could be completed (total dose; 108 M. U). These observations suggest that the type of IFN or total dose contributed to the appearance of cardiotoxicity.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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SASAKI Masaru
The Second Department of Medicine, Kurume University School of Medicine
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SUZUKI Hiroshi
The Second Department of Medicine, Kurume University School of Medicine
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Tanikawa Kyuichi
The Second Department Of Internal Medicine Kurume University School Of Medicine
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SATA Michio
the Second Department of Internal Medicine, Kurume University of Medicine
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