Evaluation of Third Generation Anti-HCV Test Kit (SYNPEPTM HCV-EIA II) Using Sera of Inhabitants from HCV Hyperendemic Area.
スポンサーリンク
概要
- 論文の詳細を見る
We examined the characteristics and usefulness of a third generation anti-HCV test kit, SYNPEP<SUP>TM</SUP> HCV-EIA II (Kyokuto Pharmaceutical Inc., Tokyo, Japan). The sera of inhabitants from a hepatitis C virus (HCV) hyperendemic area were used. The kit had even or more anti-HCV detection sensitivity and reproducibility than ORTHO HCVIII ELISA Test System<SUP>TM</SUP> (Ortho-Clinical Diagnostic K.K., Tokyo, Japan) or HCV PHA 2nd Generation<SUP>TM</SUP> (Dinabot Co., Ltd., Tokyo, Japan). SYNPEP<SUP>TM</SUP> HCV-EIA II needed less total reaction time than other EIA kits, resulting in a simple procedure. Also, HCV RNA was detected in 90% of subjects who had a 7.5 or greater cut-off index (COI) of SYNPEP<SUP>TM</SUP> HCV-EIA II kit. In conclusion, SYNPEP<SUP>TM</SUP> HCV-EIA II require cheap cost and simple procedure and it could be applied to mass screening to find out HCV RNA positive persons who may need clinical care.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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SUZUKI Hiroshi
The Second Department of Medicine, Kurume University School of Medicine
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SHIRACHI Miki
The Second Department of Internal Medicine, Kurume University School of Medicine
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Tanikawa Kyuichi
The Second Department Of Internal Medicine Kurume University School Of Medicine
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ITOH YUJI
Clinical Laboratory Department, Kurume University School of Medicine
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SATA Michio
the Second Department of Internal Medicine, Kurume University of Medicine
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FUKUIZUMI KUNITAKA
The Second Department of Medicine, Kurume University School of Medicine
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MIZUMOTO TAKAAKI
Clinical Laboratory Department, Kurume University School of Medicine
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KONDOH SHIGENOBU
Clinical Laboratory Department, Kurume University School of Medicine
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KASAHARA MICHIKO
Research and Development Department (Takahagi), Kyokuto Pharmaceutical Inc.
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MANABE SACHIKO
Research and Development Department (Takahagi), Kyokuto Pharmaceutical Inc.
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SHIRACHI MIKI
The Second Department of Medicine, Kurume University School of Medicine
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