肝疾患患者の心電図-1-

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For the purpose of elucidating the relationship between electrocardiographic changes and clinical and laboratory findings in liver diseases, 83 cases of acute and chronic hepatitis and cirrhosis (25, 20 and 38 cases respectively) including 13 cases which lapsed into hepatic coma were examined and the following results were obtained. 1) Pathological electrocardiographic findings were detected in 73.2 per cent of the whole patients, and the changes in hepatic coma were remarkable without exception. As the most common abnormalities, lowering of T-wave, ST-depression, low voltage and QT-prolongation were observed in 49.6, 29.3, 25.2 and 21.1 per cent respectively, and all these findings were more marked in the clinically severe cases. 2) No appreciable correlation was found between the electrocardiographic changes and the clinical findings such as disorders of nutrition, low blood pressure, cardiovascular murmurs, enlargement of the liver, splenomegaly, anemia and proteinuria. 3) Some parallelisms were noticed between the electrocardiographic changes and the abnormal results of liver function tests such as decrease in cholesterol ester quotient, shift to the right of the serum cobalt reaction, decrease in A/G ratio and increase in gamma globulin. Moreover, lowering of T-wave, ST-depression and low voltage were found more frequently in the group presenting abnormal serum protein patterns. Some discussions were made on the above results in reference to the concept of "hepatogene dysproteinãmische Myokardose (Wuhrmann)".
社団法人日本内科学会の論文

肝疾患患者の心電図-1-

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