GENETIC STUDIES ON THE MECHANISM OF ACQUIRED STREPTOMYCIN-RESISTANCE IN MICROORGANISMS
スポンサーリンク
概要
- 論文の詳細を見る
In studying the effect of SM on the resting cells of bacteria, no evidence was obtained which supports the specific induction of resistance by SM, because neither zero-point mutants nor end-point mutants were induced. Various facts which were thought to be explained only with the mutagenic action of this antibiotic have been shown to be more naturally explained by the spontaneous mutation with selection theory. "Relative selection" due to "relative inhibition" was emphasized in elucidating the emergence of SM-resistance in the wild population.The experiment on the development of SM-resistance in the minimal medium made it likely that the mutagenic action of SM does not operate but that the spontaneous mutation with selection would be a sole factor.In relation to the development of SM-resistance, the so-called, SM-resistance was classified into "SM-resistance" and "SM-indifference", and "SM-resistant" cells were further subdivided into "dysgonic resistant" and "eugonic resistant" cells. "SM-indifference" was considered to be a specific phenomenon for SM, while "SM-resistance" was thought to correspond to the other drug-resistance. The genetic characters of these 3 types of mutants are discussed.The author is greatly indebted to Prof. Dr. D. Ushiba for his kind sugges tions in conducting this study and for reading the manuscript of this paper.
- The Keio Journal of Medicineの論文
著者
-
Watanabe Tsutomu
Department Of Applied Physics Faculty Of Engineering The University Of Tokyo
-
WATANABE TSUTOMU
Department of Bacteriology, School of Medicine, Keio University
関連論文
- Superconductivity and a Mott Transition in a Hubbard Model on an Anisotropic Triangular Lattice(Condensed matter: electronic structure and electrical, magnetic, and optical properties)
- Variational Monte Carlo Studies of Pairing Symmetry for the t-J Model on a Triangular Lattice(Condensed Matter : Electronic Structure, Electrical, Magnetic and Optical Properties)
- UV AND X-RAY DOUBLE RESONANCE ABSORPTION USING SINGLE BUNCH OPERATION OF UNDULATOR BEAMS
- MICROSCOPIC IMAGING USING UV-VISIBLE DOUBLE RESONANCE ABSORPTION PROCESS
- OPTICAL PROPERTIES OF GRAPHITE IN THE NEAR K-ABSORPTION EDGE REGION
- STUDY OF X-RAY MICROSCOPY USING UV AND X-RAY DOUBLE RESONANCE ABSORPTION
- Successful Unrelated Cord Blood Transplantation in an Infant with Wiskott-Aldrich Syndrome following Recurrent Cytomegalovirus Disease
- K-Shell Ionization by C^+-C Collision in keV-MeV Energy Range
- Effect of Granulocyte Colony-Stimulating Factor on Bone Metabolism during Peripheral Blood Stem Cell Mobilization
- Imaging of Underground Interface Using Impulse Ultrasound and Amplitude Correlation Synthesis Processing Method
- The consistency and the longitudinal sound velocity of mountain sand versus its water content
- Ultrasonic Underground Imaging Using Amplitude Correlation Synthesizing Method
- Long-Range Interaction Potentials Involving Optically-Allowed Excited He
- Study on Measurement of Pile Driven into the Ground by Impulsive Driving Method : Industrial Apprications
- A Charge Transfer Mechanism between a Rare Gas Ion and a Diatomic Molecule; the Implication of Inner-Shell Level Mixing
- Production of Hydroxy Unsaturated Fatty Acids Using Crude Lipoxygenase Obtained from Infected Rice Plants
- Dynamic Polarizabilities and Other Dipole properties of Helium-Like Ions
- Charge Transfer Cross Sections for Kr^+-Kr and for Xe^+-Xe and the Effects of the Initial J-State in the Ions
- Bounds on Mean Excitation Energies-Lamb Shift, Stopping Power, Straggling, and Grazing Collision of High-Energy Charged Particle
- Vibrational and Rotational Excitations of HD^+ by Collision with Positive Ions
- Hemodynamic and Biochemical Responses during Exercise at the Intensity Equivalent to Lactate Threshold Elderly Women
- Collisional Excitation Transfer between Atoms in the Resonant Process
- Charge-Stripping Processes of Hydrogen-Like Ions by Collisions with Neutral Hydrogen Atoms
- Collision Theory Approach to I'+HI→I'H+I Reaction
- Semi-Classical Treatment of Symmetric Resonant Charge Transfer between Coulomb Interacting Ions
- Theoretical Considerations on Radiation-Induced Reactions of Saturated Long-Chain Hydrocarbons
- Comment on the Radiation due to Passage of an Oscillating Dipole
- ON THE LOGIC OF ARGUMENT GIVEN IN THE EINSTEIN-PODOLSKY-ROSEN PAPER
- A Remark on the Chemical Kinetics in Polymers during Irradiation
- PENNING IONIZATION OF AN AXIAL SYMMETRIC MOLECULE BY COLLISION WITH AN OPTICALLY ALLOWED EXCITED ATOM
- Nonmonotonic d_-Wave Superconductivity in Electron-Doped Cuprates Viewed from the Strong-Coupling Side(Condensed Matter: Electronic Structure, Electrical, Magnetic and Optical Properties)
- Collisional Transfer of Triplet Excitations between Helium Atoms
- Production of K-Shell Vacancies in Ion-Atom Collisions
- Diffusion Processes in Polymers under Irradiation; Polyvinyl Alcohol and CCl_4 System
- DE-EXCITATION OF p^^-He+ BY COLLISION WITH RARE-GAS ATOMS
- On the Mechanism of Electron Attachment by O_2
- Band and Mott Insulators and Superconductivity in Honeycomb-Lattice Ionic-Hubbard Model
- GENETIC STUDIES ON THE MECHANISM OF ACQUIRED STREPTOMYCIN-RESISTANCE IN MICROORGANISMS
- Charge Equilibrium of Energetic Heavy Ions in Gaseous Media : Ideal Atomic Hydrogen Gas
- Electrical double layer formed on the monolayer of crown ether compounds.
- Quantum Dielectric Fluctuation in Electronic Ferroelectricity Studied by Variational Monte-Carlo Method
- Band and Mott Insulators and Superconductivity in Honeycomb-Lattice Ionic-Hubbard Model