STUDIES ON CYCLIC NUCLEOTIDES IN THE ADRENAL GLAND V. ADENYLATE CYCLASE IN THE ADRENAL MEDULLA
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概要
- 論文の詳細を見る
Effects of various chemical agents eliciting the catecholamine-release on the adenylate cyclase-cyclic AMP generating system have been studied in the secretory process of the bovine adrenal medulla slices. Cyclic AMP levels were not affected at the interval of the maximal increase of the catecholamine-release by acetylcholine, but increased gradually some time after the end of the release/or at the beginning of the restoration of catecholamine in the medulla tissue. This delayed increase in the medullary cyclic AMP is not attributed to a direct involvement in ‘stimulus-secretion coupling process’ of the medullary secretion, but rather may be caused by release of intracellular catecholamine.
- 社団法人 日本薬理学会の論文
著者
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Shima Sumio
Department Of Biochemistry St.marianna University School Of Medicine
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Hirai Masanao
Department Of Pharmacology St. Marianna University School Of Medicine
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KAWASHIMA YOSHIKO
Department of Pharmacology, St. Marianna University School of Medicine, Kawasaki City
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KOUYAMA Hiroshi
Radioisotope Institute for Basic Medicine, St. Marianna University School of Medicine
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KAWASHIMA Yoshiko
Department of Pharmacology, St. Marianna University School of Medicine
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KAWASHIMA Yoshiko
Department of Pharmacology, Jikei University School of Medicine
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SHIMA Sumio
Department of Pharmacology, St. Marianna University School of Medicine
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