Effects of opioid peptides administered in conscious rats on the changes in blood adrenaline leves caused by immobilization stress.
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概要
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Effects of several opioid peptides administered in the lateral cerebroventricle on the changes in blood adrenaline (AD) levels were examined at 10, 20 and 30 min after the start of immobilization in conscious rats. β-Endorphin, (D-Ala<SUP>2</SUP>)-Met-enkephalinamide, morphiceptin and (D-Ala<SUP>2</SUP>, D-Leu<SUP>5</SUP>)-enkephalinamide produced significantly lower elevations of AD than the control, and the effect was enhanced by naloxone. The effect of dynorphin, however, was almost the same as that of the control.
- 公益社団法人 日本薬理学会の論文
著者
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INOUE Hakubun
Department of Pharmacology, Department of Psychoneurology, Department of Urology, Kyorin University
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Nakamura Mikio
Department Of Anatomy Jikei-kai School Of Medicine
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KAMATA Kunie
Department of Pharmacology, Department of Psychoneurology, Department of Urology, Kyorin University School of Medicine
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INABA Minoru
Department of Applied Chemistry, Graduate School of Engineering, Doshisha University
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NAKAMURA Mikio
Department of Pharmacology, Kyorin University School of Medicine
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INOUE Hakubun
Department of Psychoneurology, Kyorin University School of Medicine
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