Thrombosis of the left femoral vein in a patient with ulcerative colitis.

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A 32-year-old male with ulcerative colitis complicating thrombosis of the left femoral vein was reported. He had had remitting and relapsing symptoms of ulcerative colitis and had been treated with steroids and salicylazosulfapyridine for the previous 9 years.<BR>The patient had noted swelling of the left lower leg in November, 1984. Phlebography of the left lower limb revealed thrombosis of the left femoral vein and increased collateral veins. The results of blood coagulation tests during the presence of thrombosis were as follows : platelet count 31.7×104/μl, platelet adhesiveness 82% and platelet aggregability 84%.<BR>Platelet count, adhesiveness and aggregability were thus increased and the blood coagulation system was moderately activated. These coagulation changes associated with ulcerative colitis persisted after the thrombotic symptoms had subsided and were possibly related to the etiology of the venous thrombosis.
日本大腸肛門病学会の論文