四塩化炭素(CCl4)障害白鼠に於ける肝細胞膜機能に及ぼすSodium Taurine N-carbodithioate(TDT)の影響
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The influence of TDT administration in vivo on the changes of two enzymic activities in the liver cell membranes damaged by C Cl<SUB>4</SUB> was observed. The following results were obtained. 1) In normal rats, TDT had no significant effect on NADH-cytochrome c reductase and ATPase activities in membranes or microsomes. 2) TDT was capable of preventing not only the changes of NADH-cytochrome c reductase and ATPase activities in cell membranes produced by C Cl<SUB>4</SUB> administration, but also the leakage of NADH-cytochrome c reductase into plasma. 3) TDT did not modify the body temperature in normal rats and that induced by C Cl<SUB>4</SUB>, neither. 4) The mechanism of action of TDT was discussed.
- 社団法人 日本薬理学会の論文
社団法人 日本薬理学会 | 論文
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