Internal distribution of micro-/nano-sized ceramics and metals particles in mice
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概要
- 論文の詳細を見る
Internal distribution of several nanoparticles in mice has been investigated using scanning X-ray analytical microscopy, magnetic resonance imaging and inductively coupled plasma–atomic emission spectroscopy. According dynamic laser scattering analysis, the actual particle size of obtained metal oxide was similar to that of metal particles. The estimated diameters were ca. one micrometer. After administration through the tail vein of the mice, metal particles quickly reached some organs. The distribution ratio reached a constant value and was then maintained. On the other hand, the metal oxide particles were first localized in the spleen and lung. The concentration in the lung was decreased with post-injection time. This result suggested that the particles were temporally trapped in the lung then removed to other organs. The behaviors between metal and metal oxide were quite different even when those particles had a similar actual particle size. Therefore, the distribution behavior of particles depended on the chemical species.
- 公益社団法人 日本セラミックス協会の論文
著者
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Sato Yoshinori
Graduate School Of Environmental Studies Tohoku Univ.
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JEYADEVAN Balachandran
Graduate School of Environmental Studies, Tohoku University
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TOHJI Kazuyuki
Graduate School of Environmental Studies, Tohoku University
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Tohji Kazuyuki
Graduate School Of Environmental Studies Tohoku Univ.
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WATARI Fumio
Graduate School of Dental Medicine, Department of Biomedical, Dental Materials & Engineering, Hokkai
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ABE Shigeaki
Graduate School of Dental Medicine, Hokkaido University
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UO Motohiro
Graduate School of Dental Medicine, Hokkaido University
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ESAKI Mitsue
Graduate School of Dental Medicine, Hokkaido University
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AKASAKA Tsukasa
Graduate School of Dental Medicine, Hokkaido University
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Koyama Chika
School Of Dental Medicine Hokkaido Univ.
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Abe Shigeaki
Department Of Oral Health Science Graduate School Of Dental Medicine Hokkaido University
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Morita Manabu
Department Of Oral Health Science Hokkaido University Graduate School Of Dental Medicine
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HANEDA Koichi
Department of Electronic Materials, Ishinomaki Senshu University
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Haneda Koichi
Department Electronic Engineering Faculty Of Engineering Tohoku University:(present Address) Researc
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Jeyadevan Balachandran
Graduate School Of Engineering Tohoku University
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KIDA Ikuhiro
Graduate School of Dental Medicine, Hokkaido University
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IWADERA Nobuki
Graduate School of Dental Medicine, Hokkaido University
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MUTOH Mami
School of Dental Medicine, Hokkaido University
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KUBOKI Yoshinori
Graduate School of Dental Medicine, Hokkaido University
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YONEZAWA Tetsu
Division of Materials Science and Engineering, Graduate School of Engineering, Hokkaido University
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Yonezawa Tetsu
Division Of Materials Science And Engineering Faculty Of Engineering Hokkaido University
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Morita Manabu
Department Of Applied Biology Graduate School Of Science And Technology Kyoto Institute Of Technolog
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Uo Motohiro
Graduate School Of Dental Medicine Hokkaido Univ.
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WATARI Fumio
Graduate School of Dental Medicine, Hokkaido University
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Tohji Kazuyuki
Graduate School of Engineering, Tohoku University
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KOYAMA Chika
School of Dental Medicine, Hokkaido University
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