Recurrent Sebaceous Carcinoma in an African Hedgehog (Atelerix albiventris)
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概要
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A 1.5-year-old intact male African hedgehog (Atelerix albiventris) was presented with a firm, non-movable subcutaneous mass on ventral chest area. Microscopically, the tumor was un-encapsulated, invasive up to the muscle layer, and composed of highly pleomorphic polygonal cells arranged in variably-sized lobules. The neoplastic cells had abundant cytoplasm with vacuolation and a large pleomorphic nucleus with prominent nucleoli. Mitotic figures were frequently observed with atypical mitoses. Immunohistochemically, the neoplastic cells were strongly positive for cytokeratin, but negative for vimentin. Based on these findings, a diagnosis of sebaceous carcinoma was made. Three months after the surgery, a recurrent mass was found at the surgical site. On necropsy, the mass has penetrated the underlying intercostal musculature, without metastasis to distant organs. This is the first report of a sebaceous carcinoma in an African hedgehog.
著者
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Kim Dae-yong
Department Of Pathology College Of Veterinary Medicine Seoul National University
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Kim Hyung-jin
Department Of Neurology Sungkyunkwan University School Of Medicine Samsung Medical Center
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KIM Yong-Baek
Department of Population Health and Pathobiology, The College of Veterinary Medicine, North Carolina
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PARK Jun-Won
Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University
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OH Won-Seok
NeoDin Veterinary Science Institute
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KIM Eun-Ok
NeoDin Veterinary Science Institute
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LIM Byoung-Yong
Garam Animal Clinic
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