cDNA Cloning and mRNA Expression of Bovine GPR39
スポンサーリンク
概要
- 論文の詳細を見る
GPR39 is an orphan G protein-coupled receptor that is thought to be involved in gastrointestinal and metabolic function. In this study, we cloned bovine GPR39 cDNA that encoded 462 amino acids showing high sequence homology to other mammalian GPR39 proteins. Real-time PCR showed expression of GPR39 mRNA in the liver, kidney, abomasums, small intestine, colon, rectum and uterus, with the highest level in the abomasums. Significant promoter activity was observed within the -2.3 kb 5-upstream region of bovine GPR39 gene with human colon carcinoma-derived CACO-2 cells. These findings suggest that GPR39 may have important roles in gastrointestinal and metabolic functions in bovines as in other mammals.
- 社団法人 日本獣医学会の論文
著者
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TANAKA MINORU
Department of Thoracic Surgery, Nagoya University School of Medicine
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YAMAMOTO Ichiro
Laboratory of Animal Physiology, Graduate School of Bioagricultural Sciences, Nagoya University
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Kimura Nobuhiro
Department Of Animal Nutrition Nippon Veterinary And Animal Science University
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ARAI Toshiro
Laboratory of Veterinary Biochemistry, School of Veterinary Medicine, Nippon Veterinary and Life Sci
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Tanaka Minoru
Department Of Thoracic Surgery Nagoya University School Of Medicine
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Yamamoto Ichiro
Laboratory Of Animal Physiology Graduate School Of Bioagricultural Sciences Nagoya University
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Tanaka Minoru
Department Of Anatomy Kyoto Prefectural University Of Medicine
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Kimura Nobuhiro
Department Of Animal Science Faculty Of Applied Life Science Nippon Veterinary And Life Science University
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Yamamoto Ichiro
Department Of Veterinary Science School Of Veterinary Medicine Nippon Veterinary And Life Science University
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KIMURA Nobuhiro
Department of Animal Science, Faculty of Applied Life Science, Nippon Veterinary and Life Science University
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YAMAMOTO Ichiro
Laboratory of Veterinary Biochemistry, School of Veterinary Medicine, Nippon Veterinary and Life Science University
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