Cancer of unknown primary site in which tumor marker-oriented chemotherapy was effective and pancreatic cancer was finally confirmed at autopsy

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概要

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• We report a 47-year-old man with cancer of unknown primary site in whom pancreatic cancer was confirmed at autopsy. Although a primary lesion was not confirmed, we planned to perform tumor marker-oriented chemotherapy because pancreatic cancer was suspected as the primary lesion based on tumor markers and pathological findings from metastatic lymph node. Neither S-1 nor gemcitabine was effective. However, gemcitabine combined with low-dose cisplatin therapy resulted in a marked decrease in the size of tumors. Microscopic examination at autopsy revealed poorly differentiated adenocarcinoma in the pancreatic head, although a pancreatic mass was not clear macroscopically. © 2009 The Japanese Society of Internal Medicine.

著者

• Yasumoto Kazuo

  Division Of Surgical Oncology Cancer Research Institute Kanazawa University

• Nakanuma Yasuni

  Department Of Human Pathology Graduate School Of Medical Science Kanazawa University

• Ikeda Hiroko

  Department Of Anatomy And Histology Fukushima Medical University School Of Medicine

• Watanabe Hiroyuki

  Division Of Cardiovascular Medicine Department Of Internal Medicine Akita University School Of Medic

• YAMADA Tadaaki

  Division of Medical Oncology, Cancer Research Institute, Kanazawa University

• YANO Seiji

  Division of Medical Oncology, Cancer Research Institute, Kanazawa University

• Yamada Tadaaki

  Division Of Medical Oncology Cancer Research Institute Kanazawa University

• Ohtsubo Koushiro

  Division of Medical Oncology, Cancer Research Institute, Kanazawa University

• Mouri Hisatsugu

  Division of Medical Oncology, Cancer Research Institute, Kanazawa University

• Tsuchiyama Tomoya

  Division of Medical Oncology, Cancer Research Institute, Kanazawa University

• Yamashita Kaname

  Division of Surgical Oncology, Cancer Research Institute, Kanazawa University

• Nakanuma Yasuni

  Department of Human Pathology, Kanazawa University

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