Presence of Vertebral Fractures is Highly Associated with Hiatal Hernia and Reflux Esophagitis in Japanese Elderly People
スポンサーリンク
概要
- 論文の詳細を見る
Objective Recent studies have shown the correlation between vertebral fractures (VFs) and gastrointestinal disorders in postmenopausal women. The aim of this study was to assess the association between VFs and hiatal hernia (HH) and/or reflux esophagitis (RE) in our patient population of both men and women. Methods We analyzed retrospective data of 280 patients aged 60 years or older (140 men and 140 women, mean ± SD 73.5 years ±7.05) who had undergone upper gastrointestinal endoscopy and chest X-rays in our hospital from August 2005 to February 2006. We analyzed the correlation between the presence of VFs and the presence of HH and/or RE. Results The incidence of RE in this study was 13.9% (39/280) and that of HH was 30.0% (84/280). Among these patients, 12.1% (41/280) had VFs. The incidence of RE in patients with VFs was 24.4% (10/41) and without VFs was 12.1% (29/239), with the difference being significant between those with and without VFs (p<0.05). The incidence of HH in patients with VFs was 43.9% (18/41) and in those without VFs was 27.6% (66/239), p<0.05. We subdivided subjects into four groups: HH only group, RE only group, HH/RE group and neither condition present group. We compared the incidence of VFs among these groups. VFs were observed in 16.4% (11/67) of the HH only group, 13.6% (3/22) of the RE only group, 41.2% (7/17) of the HH/RE group and 11.5% (20/174) in the neither condition present group. There was a significant difference in the incidence of VFs between the HH/RE group and neither condition present group (p<0.05). Conclusion The presence of VFs was significantly associated with the presence of either RE or HH. This association became more significant when HH and RE were present together in elderly Japanese people.
著者
-
Watanabe Sumio
Department Of Gastroenterology Juntendo University
-
SHIMADA Yuji
Department of Biochemistry, Osaka Municipal Technical Research Institute
-
Hojo Mariko
Department Of Gastroenterology Juntendo University School Of Medicine
-
Kawabe Masato
Department Of Gastroenterology Juntendo University School Of Medicine
-
Asaoka Daisuke
Department Of Gastroenterology Juntendo University School Of Medicine
-
Nagahara Akihito
Department Of Gastroenterology Juntendo University School Of Medicine
-
Ohtaka Keiichi
Department Of Gastroenterology Juntendo University School Of Medicine
-
Kurosawa Akihiko
Department Of Gastroenterology Juntendo University School Of Medicine
-
Osada Taro
Department Of Gastroenterology Juntendo University School Of Medicine
-
Yoshizawa Takashi
Department Of Engineering Physics The University Of Electro-communications
-
ASAOKA DAISUKE
Department of Gastroenterology, Juntendo University School of Medicine
-
Kawabe Masato
Department of Gastroenterology, Juntendo University School of Medicine
-
Yoshimura Miho
Department of Gastroenterology, Juntendo University School of Medicine
関連論文
- The tumor suppressor protein PTEN inhibits rat hepatic stellate cell activation
- Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo
- Pseudocapsule Formation After Gamma Knife Radiosurgery for Trigeminal Neurinoma : Case Report
- Hamartomatous Inverted Polyp Successfully Treated by Endoscopic Submucosal Dissection
- Clinicopathological features of nonpolypoid colorectal tumors as viewed from the patients' background
- -6-THE CLINICAL SIGNIFICANCE OF EXERCISE-INDUCED ST-SEGMENT ELEVATION : Excercise Test : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Comparison of the efficacy of 400mg and 800mg of clarithromycin used with lansoprazole and amoxicillin in eradication regimens for Helicobacter pylolr infection in Japanese population
- Decreased renal expressions of heat shock protein-72 and -25 are associated with renal dysfunction in biliary cirrhotic rats
- Epimorphin expression and stellate cell status in mouse liver injury
- Genipin prevents fulminant hepatic failure resulting in reduction of lethality through the suppression of TNF-α production
- Gabexate mesilate, a synthetic protease inhibitor, attenuates carbon tetrachloride-induced liver injury in rats
- Expression of a 72-kDa heat shock protein, and its cytoprotective function, in gastric mucosa in cirrhotic rats
- The expression of Fas and Fas ligand, and the effects of interferon in chronic liver diseases with hepatitis C virus
- MECHANICAL STRETCH INCREASES PRODUCTION OF MMP1 AND DECREASES PRODUCTION OF TIMP1 AND TIMP2 IN HEPATIC STELLATE CELLS
- Mn-Metalloporphyrin Conjugated with Gd-DTPA (Gd-ATN10): Tumor Enhancement Agent for Magnetic Resonance Imaging
- Treatment of functional dyspepsia with antianxiety or antidepressive agents : systematic review
- Second-line treatment for Helicobacter pylori infection in Japan : proton pump inhibitor-based amoxicillin and metronidazole regimen
- Epithelial-mesenchymal interaction in gastric mucosal restoration
- Tasurine preserves gap junctional intercellular communication in rat hepatocytes under oxidative stress
- Relapsed duodenal ulcer after cure of Helicobacter pylori infection
- Effects of teprenone on gastric epithelial restoration in a rabbit cultured cell model
- Effects of epidermal growth factor and insulin on migration and proliferation of primary cultured rabbit gastric epithelial cells
- Multiple early esophageal cancers arising from Barrett's esophagus, and a review of cases of early adenocarcinoma in Barrett's esophagus in Japan
- Reduction of gap junction protein connexin 32 in rat atrophic gastric mucosa as an early event in carcinogenesis
- Isomer-Specific Anti-Obese and Hypolipidemic Properties of Conjugated Linoleic Acid in Obese OLETF Rats
- Ecabet sodium prevents the delay of wound repair in intestinal epithelial cells induced by hydrogen peroxide
- Novel Evidence Suggesting Clostridium difficile Is Present in Human Gut Microbiota More Frequently than Previously Suspected
- Hepatocyte-specific Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma
- ATTENUATION OF THE COLONIC DAMAGE IN EXPERIMENTAL COLITIS BY FR167653, A NOVEL SUPPRESSOR OF IL-1 AND TNF-α PRODUCTION
- CORTICOSTEROID PRETREATMENT PREVENTS SMALL INTESTINAL MUCOSAL DAMAGE INDUCED BY ACETIC ACID-PERFUSION MODEL IN RATS
- Effects of cyclosporin A on water-immersion stress-induced gastric lesion and gastric secretion in rats
- NEWLY DEVELOPED AUTOFLUORESCENCE IMAGING VIDEOSCOPE SYSTEM FOR THE DETECTION OF COLONIC NEOPLASMS
- Detection of IgA, IgM, and IgG subclasses of anti-M2 antibody by immunoblotting in autoimmune cholangitis : Is autoimmune cholangitis an early stage of primary biliary cirrhosis?
- Hepatic gene expression in hepatocyte-specific Pten deficient mice showing steatohepatitis without ethanol challenge
- Use of Selective Serotonin Reuptake Inhibitors and Upper Gastrointestinal Disease
- Efficacy of camostat mesilate against dyspepsia associated with non-alcoholic mild pancreatic disease
- A case of pseudoobstruction of the intestine associated with scleroderma dramatically responding to antibiotics
- Sucralfate prevents the delay of wound repair in intestinal epithelial cells by hydrogen peroxide through NF-κB pathway
- Assessment of Gibberella fujikuroi mating type by PCR
- Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy
- Morphological Diversity of the Colony Produced by Bacteria Proteus mirabilis
- Spatiotemporal Patterns Produced by Bacteria
- Attenuation of gastric mucosal inflammation induced by indomethacin through activation of the A_ adenosine receptor in rats
- Effect of cilostazol, a selective type-III phosphodiesterase inhibitor, on water-immersion stress-induced gastric mucosal injury in rats
- Selective A_ adenosine agonist ATL-146e attenuates acute lethal liver injury in mice
- Electronic Structures and Oxidation Potentials of Some Azulene Derivatives
- Liver diseases and metabolic syndrome
- Analysis of Where and Which Types of Proteinase Participate in Lysosomal Proteinase Processing Using Bafilomycin A1 and Hericobacter pylori Vac A Toxin
- EXTRAESOPHAGEAL MANIFESTATIONS OF GERD IN A RAT CHRONIC ACID REFLUX ESOPHAGITIS MODEL
- Ultrasound-guided percutaneous drainage may decrease the mortality of severe acute pancreatitis
- Intestinal Involvement in Wegeners Granulomatosis Diagnosed and Followed up by Double Balloon Enteroscopy
- Prolonged treatment with pegylated interferon α 2b plus ribavirin improves sustained virological response in chronic hepatitis C genotype 1 patients with late response in a clinical real-life setting in Japan
- Metabolic syndrome and gastrointestinal diseases
- Radiofrequency ablation of hepatocellular carcinoma : The feasibility of magnetic resonance imaging with gadolinium ethoxybenzyl diethylene triamine pentaacetic acid for evaluating the ablative margin
- CAvernous Hemangioma of the Adrenal Gland : MRI Appearance
- Evaluation of new subclassification of type V_I pit pattern for determining the depth and type of invasion of colorectal neoplasm
- Dissociation and dispersion of claudin-3 from the tight junction could be one of the most sensitive indicators of reflux esophagitis in a rat model of the disease
- Presence of Vertebral Fractures is Highly Associated with Hiatal Hernia and Reflux Esophagitis in Japanese Elderly People
- Osler-Weber-Rendu Disease with Esophageal Varices and Hepatic Nodular Change
- Relationship Between Endoscopic Findings and Clinical Severity in Ischemic Colitis
- m-and l-Changing Collisions of High-Rydberg Atoms with Rare-Gas Atoms
- Loss of autophagy promotes murine acetaminophen hepatotoxicity
- The Relationship between Physical Activity Level and Completion Rate of Small Bowel Examination in Patients Undergoing Capsule Endoscopy
- Ventricular Tachycardia in a Patient with Gorlin Syndrome
- Small Intestinal Follicular Lymphoma with Multiple Tumor Formations Diagnosed by Double-Balloon Enteroscopy
- Gastrointestinal Hemorrhage as the First Manifestation of Metastatic Extragonadal Choriocarcinoma
- Diaphragm-like Stricture in the Duodenum in a Patient with Systemic Sclerosis: Unrelated to Non-steroidal Anti-inflammatory Drug Use
- Obstructing Small Bowel Bezoars Due to an Agar Diet: Diagnosis Using Double Balloon Enteroscopy
- Altered expression of angiogenic factors in the VEGF-Ets-1 cascades in inflammatory bowel disease
- Cancer preventive effect of pegylatecl interferon α-2b plus ribavirin in a real-life clinical setting in Japan : PERFECT interim analysis
- Analysis of Where and Which Types of Proteinases Participate in Lysosomal Proteinase Processing Using Bafilomycin A1 and Helicobacter pylori Vac A Toxin.
- Altered expression and function of hepatic natural killer T cells in obese and diabetic KK-Ay mice