Relationship Between Endoscopic Findings and Clinical Severity in Ischemic Colitis
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概要
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Background and Aim The incidence of ischemic colitis (IC) in Japan has been increasing due to the westernization of diet and the aging population. The aim of this study was to evaluate the relationship between endoscopic findings and clinical severity in IC. Methods This retrospective analysis included 106 cases diagnosed with IC that were divided into two groups based on endoscopic findings in the acute stage: redness and erosion (RE) versus longitudinal and circumferential ulcers (LCU). The clinical variables were compared between the two groups. In addition, we investigated the risk factors of IC associated with the severity of the endoscopic findings by multivariate logistic regression analysis. Results The percentage of cases presenting abdominal pain was significantly higher in the LCU group than that in the RE group (p=0.002), as were the baseline serum CRP levels (p=0.0001). The periods of hospitalization in LCU group were longer than in the RE group (p=0.0001). Multivariate logistic regression analysis indicated that ischemic heart disease (IHD) and connective tissue disease were the independent explanatory factor associated with the endoscopic severity of IC (p<0.05). Conclusion We showed clearly that the two endoscopic classifications were accurate indicators of severity and could be used to anticipate severity of IC. Furthermore, we confirmed that IHD and connective tissue disease were the exacerbating factor associated with the severity of endoscopic findings in IC.
著者
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Watanabe Sumio
Department Of Gastroenterology Juntendo University
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SAKAMOTO NAOTO
Department of Gastroenterology, Juntendo University, School of Medicine
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Beppu Kazuko
Department Of Gastroenterology Juntendo University School Of Medicine
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Terai Takeshi
Department Of Gastroenterology Juntendo University School Of Medicine
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Ogihara Tatsuo
Department Of Gastroenterology Juntendo University School Of Medicine
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Otaka Michiro
Department Of Gastroenterology Akita University School Of Medicine
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Nagahara Akihito
Department Of Gastroenterology Juntendo University School Of Medicine
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Shibuya Tomoyoshi
Department Of Gastroenterology Juntendo University School Of Medicine
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Osada Taro
Department Of Gastroenterology Juntendo University School Of Medicine
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Matsumoto Kenshi
Department of Advanced Nanostructured Materials Science and Technology, Kagoshima University
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Otaka Michiro
Department of Gastroenterology, Juntendo University, School of Medicine, Japan
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Terai Takeshi
Department of Gastroenterology, Juntendo University, School of Medicine, Japan
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Sakamoto Naoto
Department of Gastroenterology, Juntendo University, School of Medicine, Japan
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Sakamoto Naoto
Department of Gastroenterology, Juntendo University School of Medicine
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Shibuya Tomoyoshi
Department of Gastroenterology, Juntendo University, School of Medicine, Japan
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Beppu Kazuko
Department of Gastroenterology, Juntendo University, School of Medicine, Japan
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