Amiodarone Pulmonary Toxicity: A Patient with Three Recurrences of Pulmonary Toxicity and Consideration of the Probable Risk for Relapse
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概要
- 論文の詳細を見る
A 44-year-old man was treated with amiodarone for dilated cardiomyopathy. After 53 months, he developed amiodarone-induced interstitial pneumonia. Amiodarone treatment was terminated, and the patient was given corticosteroids. These treatments were effective. However, pneumonitis recurred whenever prednisolone was reduced to less than 5 mg per day. Considering the patients background characteristics, we considered his body mass index (BMI, kg/m2) and found his to be high. When four additional patients with amiodarone pulmonary toxicity were reviewed at our institute, a correlation between BMI and the duration of shadow disappearance was found (R2=0.8695). Because amiodarone is lipophilic, the patients high BMI might have influenced the repeated appearance of pulmonary toxicity.
- 社団法人 日本内科学会の論文
著者
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Okayasu Kaori
Department of Integrated Pulmonology, Tokyo Medical and Dental University
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Okayasu Kaori
東京医科歯科大学 呼吸器内科
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Okayasu Kaori
Department Of Integrated Pulmonology Tokyo Medical And Dental University
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Takeda Yuichiro
Department of Respiratory Medicine, International Medical Center of Japan
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Kojima Jun
Department of Respiratory Medicine, International Medical Center of Japan
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Yoshizawa Atsuto
Department of Respiratory Medicine, International Medical Center of Japan
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Kobayashi Nobuyuki
Department of Respiratory Medicine, International Medical Center of Japan
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Sugiyama Haruhito
Department of Respiratory Medicine, International Medical Center of Japan
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Kudo Koichiro
Disease Control and Prevention Center, International Medical Center of Japan
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Kudo Koichiro
Disease Control And Prevention Center International Medical Center Of Japan
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Takeda Yuichiro
Department Of Respiratory Medicine International Medical Center Of Japan
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Yoshizawa Atsuto
Department Of Pulmonology International Medical Center Of Japan
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Sugiyama Haruhito
Department Of Pulmonology The International Medical Center Of Japan
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Kojima Jun
Department Of Crystalline Materials Science School Of Engineering Nagoya University
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Kobayashi Nobuyuki
Department Of Applied Physics Faculty Of Engineering Toyama University
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Okayasu Kaori
Department of Respiratory Medicine, International Medical Center of Japan
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