A Case of Bucillamine-induced Interstitial Pneumonia with Positive Lymphocyte Stimulation Test for Bucillamine Using Bronchoalveolar Lavage Lymphocytes
スポンサーリンク
概要
- 論文の詳細を見る
A 64-year-old woman with rheumatoid arthritis and treated with bucillamine presented with a productive cough. No obvious infiltration was detected in chest radiography, but CT revealed patchy ground glass opacities in bilateral lung fields. Her serum KL-6 level was elevated and transbronchial lung biopsy showed interstitial pneumonia. Drug lymphocyte stimulation test (DLST) for bucillamine was negative for blood lymphocytes, but positive for bronchoalveolar lavage (BAL) lymphocytes. The pneumonitis improved after the cessation of bucillamine. We therefore made a diagnosis of bucillamine-induced interstitial pneumonia. DLST with BAL lymphocytes is thus suggested to be useful for such diagnoses.
著者
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Fukuda Yuh
Department Of Analytic Human Pathology Nippon Medical School
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NEI Takahito
Department of Internal Medicine Nippon Medical School
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Abe Shinji
Department Of Clinical Pharmacy Tokushima University Hospital
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Nakayama Tomoko
Department Of Pathology Nippon Medical School Tokyo And Brain Science Institute Riken
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FUKUDA Yuh
Department of Analytic Human Pathology, Nippon Medical School
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SAITO Yoshinobu
Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science
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Saito Yoshinobu
Department of Internal Medicine, Divisions of Pulmonary Medicine, Infectious Diseases, and Oncology, Nippon Medical School
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Kudoh Shoji
Department of Internal Medicine (Divisions of Pulmonary Medicine, Infectious Diseases, and Oncology), Nippon Medical School
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Usuki Jiro
Department of Internal Medicine (Divisions of Pulmonary Medicine, Infectious Diseases, and Oncology), Nippon Medical School
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Usuki Jiro
Department of Internal Medicine, Divisions of Pulmonary Medicine, Infectious Diseases, and Oncology, Nippon Medical School
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Azuma Arata
Department of Internal Medicine (Divisions of Pulmonary Medicine, Infectious Diseases, and Oncology), Nippon Medical School
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Azuma Arata
Department of Internal Medicine, Divisions of Pulmonary Medicine, Infectious Diseases, and Oncology, Nippon Medical School
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Nei Takahito
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan
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Nakayama Tomoko
Department of Analytic Human Pathology, Nippon Medical School
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Abe Shinji
Department of Internal Medicine, Divisions of Pulmonary Medicine, Infectious Diseases, and Oncology, Nippon Medical School
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