Excess Accumulation of Risk Factors in Ischemic Heart Disease
スポンサーリンク
概要
- 論文の詳細を見る
Though multiple risk factors are commonly observed in patients with ischemic heart disease and associated with an increased risk of developing IHD, it has not yet been proven that risk factors actually occur in combination more frequently than by chance alone. We tested the hypothesis that if some risk factors occur in combination, the actual incidences will be higher than the predicted ones which were calculated on the assumption that each risk factor occurs independently and in combination as a result of coincidence. One hundred consecutive patients were included in this study. All had significant stenosis or occlusion of a coronary artery. The ages ranged from 50 to 69 years and only males were studied. From the incidences of the well-established risk factors in IHD: hypertension, impaired glucose tolerance or diabetes mellitus, hypertriglyceridemia, obesity and hypercholesterolemia, we determined the actual incidences of combinations of risk factors and compared these with the predicted incidences, which were the probability calculated from each risk factor. Some of the combinations of 2 to 4 risk factors were found significantly more often than the predicted ones. Though not significant, the reverse was the case in the actual incidence of patients having no risk factors. Some combinations of well-known risk factors were found more often than the predicted risk factors from the probability and showed a tendency to cluster in coronary artery disease patients. Some linking factor must be involved in this type of occurrence of risk factors.
- Japanese Heart Journal Associationの論文
著者
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AIZAWA Yoshifusa
Division of Cardiology, Niigata University Graduate School of Medical and Dental Sciences
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Watanabe Hiroshi
Division of Infectious Diseases, Department of Infectious Medicine, Kurume University School of Medi
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Aizawa Yoshiyasu
新潟大学 医歯学総合研究科循環器学
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Fukunaga Hiroshi
Divisions of Cardiology
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Aizawa Yoshiyasu
Division of Cardiology, Niigata University Graduate School of Medical and Dental Science
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Watanabe Satoru
Division of Cardiology, Niigata University Graduate School of Medical and Dental Science
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Fukunaga Hiroshi
Division Of Cardiology Niigata University Graduate School Of Medical & Dental Sciences
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Aizawa Yoshifusa
Division Of Cardiology First Department Of Internal Medicine Niigata University Graduate School Of M
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Watanabe Satoru
Division Of Cardiology Hematology And Endocrinology
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Watanabe Hiroshi
Division Of Cardiology Hemotology And Endocrinology Niigata University Graduate School Of Medical And Dental Science
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Fukunaga Hiroshi
Division of Cardiology, Niigata University Graduate School of Medical and Dental Science
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