Evaluation of Inhibitory Effects of Vegetables and Herbs on Hyaluronidase and Identification of Rosmarinic Acid as a Hyaluronidase Inhibitor in Lemon Balm (Melissa officinalis L.)
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概要
- 論文の詳細を見る
The inhibitory effects of 46 vegetable and herb extracts on hyaluronidase (EC 3.2.1.35), which is known to be related to inflammation and involved in migration of tumor cells, were examined. Twenty-two extracts showed inhibitory activity, and the extracts of 8 Labiatae plants and borage demonstrated potent inhibition of hyaluronidase. The hyaluronidase-inhibitory compound was isolated from the MeOH extract of leaves of lemon balm, which showed the strongest inhibition among them, by a combination of partition between solvents, Amberlite XAD-7 column chromatography and ODS-HPLC. Mostly on the basis of spectrometric techniques, the hyaluronidase inhibitor in lemon balm was identified with rosmarinic acid.
- 社団法人 日本食品科学工学会の論文
- 2000-02-01
著者
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Azuma Keiko
National Food Research Institute
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Azuma Keiko
National Research Institute Of Vegetables Ornamental Plants And Tea (nivot) Ministry Of Agriculture
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YAMAGUCHI Yuichi
National Research Institute of Vegetables, Ornamental Plants and Tea
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IPPOUSHI Katsunari
National Research Institute of Vegetables, Ornamental Plants and Tea (NIVOT), Ministry of Agricultur
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ITOU Hidekazu
National Research Institute of Vegetables, Ornamental Plants and Tea (NIVOT), Ministry of Agricultur
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HIGASHIO Hisao
National Research Institute of Vegetables, Ornamental Plants and Tea (NIVOT), Ministry of Agricultur
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Itou Hidekazu
National Research Institute Of Vegetables Ornamental Plants And Tea (nivot) Ministry Of Agriculture
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Higashio Hisao
National Research Institute Of Vegetables Ornamental Plants And Tea (nivot) Ministry Of Agriculture
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Higashio Hisao
National Research Institute Of Vegetables Ornamental Plants And Tea
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Azuma Keiko
National Food Res. Inst. Ibaraki Jpn
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Ippoushi Katsunari
National Inst. Of Vegetable And Tea Sci. National Agriculture And Food Res. Organization
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Ippoushi Katsunari
National Research Institute Of Vegetables Ornamental Plants And Tea (nivot) Ministry Of Agriculture
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Yamaguchi Yuichi
National Research Institute Of Vegetables Ornamental Plants And Tea (nivot) Ministry Of Agriculture
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Yamaguchi Yuichi
National Research Institute Of Vegetables Ornamental Plants And Tea
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