A Role of Androgen Receptor Protein in Cell Growth of an Androgen-Independent Prostate Cancer Cell Line

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概要

• 論文の詳細を見る

• Prostate cancer, which develops due to androgen and is initially responsive to androgen deprivation therapy, often comes to acquire androgen deprivation therapy resistance in short order. We investigated the role of androgen receptor (AR) protein in an androgen-independent prostate cancer cell line using AR ligands and AR siRNA. Although the androgen-independent cell line scarcely responded to AR ligands, their growth was attenuated by ablation of AR protein by siRNA.

• 社団法人 日本農芸化学会の論文
• 2005-11-23

著者

• Kato Shigeaki

  Institute Of Molecular And Cellular Biosciences The University Of Tokyo

• TAKEYAMA Ken-ichi

  Institute of Molecular and Cellular Biosciences, The University of Tokyo

• TANIGUCHI Nobuaki

  Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co., Ltd.

• Takeyama Ken-ichi

  Inst. Of Molecular And Cellular Biosciences Univ. Of Tokyo

• Takeyama Ken-ichi

  Institute Of Molecular And Cellular Biosciences The University Of Tokyo

• Taniguchi Nobuaki

  Drug Discovery Research Astellas Pharma Inc.

• Shibasaki Masayuki

  Drug Discovery Research Astellas Pharma Inc.

• Kato Shigeaki

  Institute Of Molecular And Cellular Bioscience University Of Tokyo

• Kato Shigeaki

  Exploratory Res. For Advanced Technol. (erato) Japan Sci. And Technol. Agency (jst)

• Kudoh Masafumi

  Drug Discovery Research Astellas Pharma Inc.

• FURUTANI Takashi

  Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co., Ltd.

• FURUTANI Takashi

  Drug Discovery Research, Astellas Pharma Inc.

• KOUTOKU Hiroshi

  Drug Discovery Research, Astellas Pharma Inc.

• ITO Saya

  Institute of Molecular and Cellular Biosciences, University of Tokyo

• SUZUKI Eriko

  Institute of Molecular and Cellular Biosciences, University of Tokyo

• SHIKAMA Hisataka

  Drug Discovery Research, Astellas Pharma Inc.

• Suzuki Eriko

  Institute Of Molecular And Cellular Biosciences University Of Tokyo

• Furutani Takashi

  Drug Discovery Research Astellas Pharma Inc.

• Ito Saya

  Institute Of Molecular And Cellular Biosciences University Of Tokyo

• Shikama Hisataka

  Drug Discovery Research Astellas Pharma Inc.

• Koutoku Hiroshi

  Drug Discovery Research Astellas Pharma Inc.

• Kato Shigeaki

  Institute for Chemical Research, Kyoto University

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