成熟期中期のラット足底筋に対する走トレーニングの影響

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We studied the effects of running training on myosin heavy chain (MyHC) isoform compositionin 16 female mature Fischer 344 rats (12 month old). The animals were divided into two groups:sedentary (S; n = 7) or run (R; n = 9) group. Animals in the R group were trained with treadmillrunning (30 m/min, 60 min/day and 5 days/wk) for 8 weeks. After 8-weeks of training, the plantarismuscle (PLA) was isolated, and crude myosin was prepared. MyHC isoform composition was analyzedby sodium dodecyl sulfate polyaclylamidegel electrophoresis (SDS-PAGE).Body weights in both groups increased significantly during the training period. However, the finalbody weights of each group were not significantly different. PLA weight and relative PLA weight ofthe R group were significantly higher than those in the S group.No statistical difference was found in the compositions of the MyHC I and IId isoforms in eithergroup. However, the R group value for the type IIa MyHC isoform was higher than that of the Sgroup and the type IIb MyHC isoform value for the R group was relatively lower than that of the Sgroup.These results indicated that the MyHC isoform composition of the PLA muscle changed withrunning training. We conclude that running training during the middle period of maturation affectedmuscle contractile protein metabolism.
久留米大学健康・スポーツ科学センターの論文