雌性Fischer344系ラットヒラメ筋におけるミオシン重鎖アイソフォーム構成比の加齢変化

概要

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We studied a change of myosin heavy chain (MyHC) isoform composition by aging in female Fischer344 rats soleus muscles. Three (N=6)-, six (N=6)-, twelve (N=6)-, twenty (N=7)- and twenty-sevens (N=6)-month old female rats were examined. The weight of soleus muscle was not changed with aging. The relative weight of soleus muscle was not changed from 3-month-old to 12-month-old. But, the relative weight in 20- and 27-month old was significantly lower than 3- month old. The existence of type II a MyHC was identified, and this isoform composition was not different by 12-month old from 3-month old. But, it was not possible to identified existence of type II a MyHC in 20- and 27-month old. These results indicated that the changes by aging would be different from about 20-month in female Fischer344 rat soleus muscle.
久留米大学の論文
1998-07-01