ラット腓腹筋外側部表層のミオシン重鎖アイソフォーム構成に及ぼす持久性走トレーニングの影響 : 単一筋線維での検討

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The effect of endurance running training on the myosin heavy chain (MyHC) isoform composition was investigated in the 19-week-old fevale Fischer344 rats. Animals were divided into two groups; sedentary (S; N=7) or endurance running training (E; N=6) group. The rats of group E were trained by treadmill running (30m/min, 60min/day, 5day/wk, and 8wks). The fastrocnemius muscles (GAS), the heart and the perirenal adipose tissue (PERI) werte removed and weighted. The single fibers were dissected from superficial portion of lateral GAS. The single fiber type was determined by MyHC composition. The GAS weight and the relative GAS weight of group E were sifnificantly higher than group S. On the other hand. The heart weight and the relative heart weight of group E were significhatly higher than troup S. On the other hand, The PERI weight and the relative PERI weight of group E were significhantly lower than group S. The mean cross sectinal area and succinate composition of single fiber, the pure (IIB or IID) and hybrid (Iib+D or IID+B) fiber was no statistically difference between two groups. These results indicate that endurance running training couses the increase of muscle and heart weight, but dose not clear effect on the composition of single fiber in GAS.
久留米大学の論文