排尿障害に対するFlavoxate錠の臨床的効果について--二重盲検法による検討

概要

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Flavoxate was administered to the patients complaining of frequent urination, feeling of residual urine, unpleasant sensation on urination or burning on urination. The obvious urinary tract infection was excluded from the study. The clinical investigation was carried out by a double blind study with lactose as a placebo. 1. The study cases consisted of 54 Flavoxate and 51 placebo, totally 105. 2. Frequent urination improved remarkably in the Flavoxate group compared with the placebo group. 3. Feeling of residual urine also improved better in the Flavoxate group. 4. No difference was proved as to improvement of unpleasant feeling or burning on urination between the two groups. 5. In general evaluation, the Flavoxate group showed more excellent response than the control group. 6. Side effect was observed in 5 % of the Flavoxate and 5.9 % of the placebo group. This was not a significant difference. Side effect was very slight in all the cases.
泌尿器科紀要刊行会の論文