IsoferritinのHybrid構造と免疫学的特性に関する研究

概要

論文の詳細を見る
Effects of long term exposure to trichloroethylene on memory and learning in rats were investigated in a dose-effect relationship through operant behavior (FR 30, DRL 12 sec schedule). Rats were exposed to trichloroethylene, at concentrations of 2,600, 5,000 and 8,000 ppm for 30 min a day, 6 days a week for 80 out of 93 days. Retention, relearning and extinction of FR 30, acquisition of DRL 12 sec schedule, spontaneous activity and emotionality were measured. The only chronic effect obtained was a slight impairment of the learning faculty. No effects were detected on memory, emotionality, spontaneous activity and boby weight. The author propose the use of a checking system involving the test battery described in this paper for the detection of certain environmental contaminants on the central nervous system, especially on memory and learning.
札幌医科大学の論文
1979-08-01