紫根の研究(第1報) : 硬紫根中の新微量色素の構造と2種類のShikonin誘導体異性体の単離

概要

論文の詳細を見る
From the root of Lithospermum erythrorhizon SIEB. et ZUCC., eight naphthoquinone pigments, i.e. shikonin (I), acetylshikonin (II), β-hydroxyisovalerylshikonin (III), deoxyshikonin (IV), α-methyl-n-butyrylshikonin (VII) and isovalerylshikonin (VIII), and two new pigments, lithospermidins A and B were isolated. Compounds (VII) and (VIII) were fcr the first time individually isolated and crystallized by means of high-speed liquid chromatography. The structures of those lithospermidins A and B were determined, by comparison of their visible-ultraviolet, infrared, mass and proton nuclear magnetic resonance spectra with those of other six pigments, to be 5,8-dihydroxy-2-(1-α-methyl-n-butyryloxy-4-methyl-4-hydroxy-2-pentenyl)-1,4-na-phthoquinone (IX) and 5,8-dihydroxy-2-(1-isovaleryloxy-4-methyl-4-hydroxy-2-pentenyl)-1,4-na-phtho quinone (X) respectively.
1982-06-20