MNM-1A-1 電気的1分子検出のためのナノ流体デバイスの研究(セッション 1A マイクロ・ナノスケールバイオ計測と医用応用)

概要

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We are trying to realize electrical single-molecule detection in nanofluidic device that electrically identifies single biomolecules one by one, as our continuous effort to realize single molecular processing technology. The physical size exclusion effect of the nanochannel serves as the underlying principle for the single-molecule detection. Because the cross-section of the nanochannel can be as small as the size of a biomolecule, only a single molecule can pass into the nanochannel at one time. Herein we developed a simple nanofluidic device having a nanometer-height straight channel that is functionalized with a pair of electrodes for electrical sensing of aqueous solution as the first step for the future single-molecule sensing. The fabrication method and the performance of electrical sensing was primitively evaluated by measuring the current when a sodium chloride solution used as a sample.
一般社団法人日本機械学会の論文
2010-10-12