Lactobacillus-mediated RNA interference in nematode(MEDICAL BIOTECHNOLOGY)
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概要
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We engineered Lactobacillus paracasei to produce a dsRNA that would trigger RNAi-induced silencing of an essential gene in the nematode Caenorhabditis elegans. The dsRNA-expressing L. paracasei can be used in experiments conducted on culture plates and may also be used as an orally administrable dsRNA carrier for humans and other mammals.
著者
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OHTSUKI Takashi
Department of Applied Chemistry and Biotechnology, Faculty of Engineering, Yamanashi University
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Kuwahara Ai
Department of Bioscience and Biotechnology, Okayama University
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Arita Masashi
Department of Bioscience and Biotechnology, Okayama University
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Kushiro Akira
Yakult Central Institute for Microbiological Research
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Sakube Yasuji
Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University
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Sisido Masahiko
Department of Bioscience and Biotechnology, Okayama University
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Ohtsuki Takashi
Department Of Applied Chemistry And Biotechnology Faculty Of Engineering University Of Yamanashi
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Sisido Masahiko
Department Of Bioscience And Biotechnology Okayama University
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Sakube Yasuji
Division Of Bioscience Graduate School Of Natural Science And Technology Okayama University
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Kuwahara Ai
Department Of Bioscience And Biotechnology Okayama University
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Arita Masashi
Department Of Bioscience And Biotechnology Okayama University
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Sisido Masahiko
Department Of Bioengineering Science Faculty Of Engineering Okayama University
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Ohtsuki Takashi
Department Of Bioscience And Biotechnology Okayama University
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Ohtsuki Takashi
Department Of Applied Biology Faculty Of Textile Science And Technology Shinsyu University
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