ウグイ網膜の三相性水平細胞への視細胞の入力の解析(橋本葉子教授退任記念論文集)

概要

論文の詳細を見る
Photo responses of triphasic horizontal cells (C3HC's) in the retina of the Japanese dace show quite different patterns in the light and dark adaptated states. We have tried to analyze the photoreceptor inputs to these triphasic horizontal cells. Dark adapted, isolated retinas were used. Responses were recorded intracellularly and some of the cells were morphologically identified with lucifer yellow injection. In the dark adapted state, depolarization to monochromatic light flashes ranged between 440 and 600 nm. The maximal depolarizing response was obtainded around at 520 nm. Even dim white flashes, could produce depolarizing responses in C3HC's, when dark adapted. The thresholds of the responses were almost identical to those of rod horizontal cells. In contrast, under light adaptation, the depolarizing responses disappeared and all the responses were hyperpolarizing. We conclude that the dynamic range of the responses is more than 5 log units. These results suggest that C3HC's receive both rod and cone inputs. This is consistent with the morphological structure revealed by electron microscopic studies, which show that both rods and cones make synaptic contacts with C3HC's.
東京女子医科大学の論文
1997-05-25