3歳児の喘息様症状の有症率とそれに関連する諸因子の評価

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In order to evaluate the prevalence of asthmatic symptoms and their related risk factors, a questionnaire survey and measurements of urinary cotinine, urinary hydroxyproline and exposed nitrogen dioxide were performed in children at 3 years of age. Results of this study were as follows: (1) The prevalence of asthmatic symptoms was 7.6% (8.6% in male, 6.6% in female) in the subjects. (2) Significantly high prevalence of asthmatic symptoms was observed in infants who have a familial history of allergic diseases, complications in allergic diseases except for bronchial asthma and a past history of bronchitis or pneumonia. (3) Although urinary cotinine/creatinine ratio was a useful biochemical indicator of passive smoking, no significant difference in the ratio was observed between asthmatic and non-asthmatic infants. (4) Urinary hydroxyproline/creatinine ratio was examined as a biochemical indicator of the degree of atmospheric and indoor air pollution. No significant difference was observed between asthmatic and non-asthmatic infants nor between passive and non-passive smoking infants; the distance of the children' s homes from heavy traffic was not significantly associated with the biochemical indicator. (5) Personal exposure to nitrogen dioxide was higher in infants whose home had heating appara tus with no ventiduct than those whose home had ventiduct. (6) There was no significant difference for growth between asthmatic and non-asthmatic infants. In addition to the questionnaire survey, we conducted at the same time the objective evaluation of the degree of the personal exposure to the atmoshperic and indoor air pollution, such as nitrogen dioxide and environmental tobacco smoke. In order to enhance reliability of the survey, it is desired to conduct the objective evaluation of the survey results.
東京女子医科大学の論文
2001-10-25

3歳児の喘息様症状の有症率とそれに関連する諸因子の評価

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