CAUSES OF CONTACT DERMATITIS FROM LEATHER WORK GLOVES

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概要

• 論文の詳細を見る

• A group of electricians wearing leather work gloves in summer developed contact dermatitis, a form of eczema, between the thumb and forefinger. Laboratory animals were employed for a subcutaneous injection test using extract from the work gloves, a skin irritant test by extract coating and the maximization method. The results obtained were as follows. 1. The infection-type skin irritation test revealed a reaction to the leather glove extract. The reaction was greater for an extract with a low pH and high trivalent chromium concentration. To investigate the stimulus by acidic conditions only, sulfuric acid was added to a physiological saline solution, pH was put at the same level as the leather glove extract, and the results were again positive. Also, using a chromium sulfate solution adjusted to the same amount of trivalent chromium as in the glove extract, we found once again to be positive. 2. The skin irritation test by the extract coating method revealed a positive reaction. The minutely injured mice during depilation especially showed a strong reaction. 3. The skin sensitization test with the maximization approach resulted in a negative reaction with both the extract and the chromium sulfate. Thus, yje results with laboratory animals suggested that the dermatoses from using leather work gloves was caused by both physical irritation of the skin, and the seat-based leather glove extract incorporating chromium sulfate with low pH levels.

• 名古屋市立大学の論文
• 1982-03-30

著者

• 松下 武彦

  Environmental Science Section Nagoya City Health Research Institute

• 青山 光子

  Department Of Hygiene Nagoya City University Medical School

• 成瀬 正春

  Environmental Science Section, Nagoya City Health Research Institute

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