Egg Activation
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概要
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Early in the fertilization process a series of events occurs, including depolarization of the egg plasma membrane, sperm penetration, release (exocytosis) of the contents of cortical vesicles (alveoli), formation of the perivitelline space, and resumption of meiotic division. Eggs undergoing these fertilization reactions, particularly exocytosis, are called activated eggs. Unfertilized eggs in most teleosts are activated not only by immersion in isotonic saline or freshwater resembling spawning environment, but also by chemical or physical stimulants (Yamamoto, 1958, 1961). In the egg activation, a number of functional proteins may be activated by proteolytic cleavage of a terminal peptide (Nakano, 1969) and by phosphorylation or dephosphorylation of functional proteins. Such phenomena induced by fertilization should also be observed in eggs parthenogenetically activated by chemical or physical stimuli, even though most of these eggs do not develop further. The present review deals with the cortical reaction events of egg activation, mainly in the medaka.
- 名古屋大学の論文
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関連論文
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