ビタミンと認知症(<特集>ビタミンと高齢者[I])

概要

論文の詳細を見る
Cognitive impairment and dementia increase with ageing. Considering the late age of onset it is reasonable to consider that environmental factors are as likely to contribute to the dementia. Diet and ultimately nutrition are major environmental factors that may play a role in this late-onset disease. However, environmental risk factors have not been identified with certainly. Alzheimer's disease (AD) is the most common cause of dementia. Epidemiological studies have explored the associations between nutrients and AD, and some studies suggest that high intake of vitamin C, E, B_6 and B_<12>, and folate are related to a low risk of AD, but reports are inconsistent. Epidemiological studies assessing the effect of vitamin E in healthy individuals have yielded conflicting results. The objective in this paper is to review data relating to the effects of antioxidant vitamins and homocysteine-related vitamins (B-vitamins) on cognitive decline and dementia, especially AD.
日本ビタミン学会の論文
2009-07-25