皮膚機能ノ免疫學的研究 : 第3編 經膚免疫療法ニ關スル研究
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The author was able to prove in the tests stated in the former papers that the skin of rabbits when slightly rubbed preliminarily with some organic solvents, as petroleum-benzine or benzene, it promoted the percutaneous absorption of the antigen-ointment containning either soluble antigen such as immuno-serum of typhoid or an unsoluble one such as typhoid fever vaccine and accelerated the percutaneous immunization accordingly. The slight rubbing with some organic solvents influenced, furthermore, stimulatively the function of the reticulohistiocyten system of the skin and acted beneficially towards the establishment of the immunization of the local skin. These facts suggested to the author that the percutaneous immuno-therapy may be worthy of being applied clinically. He, therefore, first began to experiment with animals.
- 京都府立医科大学の論文
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