The neurobiology of suicide

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概要

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• The current state of knowledge regarding the neurobiology of suicide was reviewed. At least 3 neurobiological systems are involved in the pathophysiology of suicidal behavior. Dysfunction of the serotonergic system (trait-dependent system) and hyperactivity of the noradrenergic system and hypothalamic-pituitary-adrenal axis (state-dependent systems) appear to be included. Increasing evidence points to an overlap between neurobiological and cognitive psychological approaches to understanding suicidal behavior. A better understanding of the neurobiology of suicide can help detect at risk populations and help develop better preventive interventions. Because suicide continues to be a major public health problem, further study is clearly needed, including research on the synergic effect of medical and psychosocial approaches.

• 近畿大学の論文

著者

• Shirakawa Osamu

  Department Of Neuropsychiatry Kinki University School Of Medicine

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