Pineal Germinoma With a Prominent Epithelioid Cell Granuloma Component
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概要
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A 20-year-old man presented with a rare case of germinoma with a large component of epithelioid cell granuloma manifesting as oscillopsia. Magnetic resonance imaging demonstrated a mass in the pineal region with homogeneous enhancement with gadolinium. Craniotomy was performed, ending in biopsy. The initial histological diagnosis was epithelioid cell granuloma, but systemic investigation detected no evidence of granulomatous disorder. A revised diagnosis of germinoma was based on positive immunohistochemical staining for placental alkaline phosphatase (PLAP) and c-kit. Histological diagnosis is sometimes incorrect if granulomatous reaction is dominant. Immunohistochemical staining for PLAP and c-kit should be performed if germinoma is clinically suspected.
- 社団法人日本脳神経外科学会の論文
- 2008-12-15
著者
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ABE Toshiaki
Department of Neurosurgery, The Jikei University School of Medicine
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NAKAJIMA Masato
Department of Mechanical Engineering, Nagaoka University of Technology
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Fukunaga Masaharu
Department Of Pathology The Jikei University School Of Medicine
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Abe Toshiaki
Department Of Neurosurgery Jikei University School Of Medicine
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Nakajima Masato
Department Of Cardiovascular Surgery Yamanashi Central Hospital
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Fukunaga Masaharu
Department Of Pathology Jikei University School Of Medicine
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Fukunaga Masaharu
Department Of Pathology Jikei University School Of Medicine Daisan Hospital
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MORI Ryosuke
Department of Neurosurgery, Jikei University School of Medicine, Daisan Hospital
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SAKAI Haruo
Department of Neurosurgery, Jikei University School of Medicine, Daisan Hospital
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Sakai Haruo
Department Of Neurosurgery Jikei University School Of Medicine Daisan Hospital
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Mori Ryosuke
Department Of Neurosurgery Jikei University School Of Medicine Daisan Hospital
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Nakajima Masato
Department Of Neurosurgery Jikei University School Of Medicine Daisan Hospital
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Nakajima Masato
Department Of Applied Physics Waseda University
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