Is Sodium Alginate an Alternative Hemostatic Material in the Tooth Extraction Socket?
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概要
- 論文の詳細を見る
Alginate has been used in wound dressing and tissue engineering. In this study, our designed alginate sponge was examined for use as an optimal occlusion material. Alginate powder was mixed in double-distilled water (3.0% w/v), sterilized and lyophilized to become a sponge. Sixty Wistar rats were undergone the right mandibular incisor extraction and divided into 3 groups: the first group received an alginate sponge; the second received a gelatin sponge; and the third was untreated. The mandibles were retrieved after 1, 2, 4 and 8 weeks and subjected for bleeding measurement, radiographic and histological analyses. Alginate and Gelatin groups showed significantly shorter bleeding time until hemostasis than control. In Alginate group, as well as the other groups, bone formation was observed from 2 weeks post operation. The extraction socket receiving alginate was finally filled with osteoblasts and bone, suggesting that alginate might be considered as a candidate for not only cartilage but bone generation.
- 日本再生歯科医学会の論文
- 2008-03-30
著者
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Ohya K
Section Of Pharmacology Department Of Hard Tissue Engineering Graduate School Tokyo Medical And Dent
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Ohya K
Tokyo Medical And Dental Univ. Tokyo Jpn
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Ohya Keiichi
Pharmacology Department Of Hard Tissue Engineering Graduate School Tokyo Medical And Dental Universi
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Ohya Keiichi
Pharmacology Department Of Hard Tissue Engineering Graduate School Tokyo Medical And Dental Universi
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Ohya K
Tokyo Medical And Dental Univ.
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Goto Nobuhiro
Oral Implantology And Regenerative Dental Medicine Department Of Masticatory Function Rehabilitation
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Ohya Keiichi
Department Of Hard Tissue Engineering Section Of Pharmacology Tokyo Medical And Dental University Gr
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Kuroda Shinji
Section Of Oral Implantology And Regenerative Dental Medicine Department Of Masticatory Function Reh
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Kasugai S
Section Of Oral Implantology And Regenerative Dental Medicine Department Of Masticatory Function Reh
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Kasugai Shohei
Oral Implantology And Regenerative Dental Medicine Tokyo Medical And Dental University
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Kasugai Shohei
Oral Implantology And Regenerative Dental Medicine
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KANEDA Kazutaka
Oral Implantology and Regenerative Dental Medicine, Department of Masticatory Function Rehabilitatio
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KURODA Shinji
Oral Implantology and Regenerative Dental Medicine, Department of Masticatory Function Rehabilitatio
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SATO Daisuke
Oral Implantology and Regenerative Dental Medicine, Department of Masticatory Function Rehabilitatio
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Kaneda Kazutaka
Oral Implantology And Regenerative Dental Medicine Department Of Masticatory Function Rehabilitation
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Ohya Keiichi
Pharmacology Department Of Hard Tissue Engineering Division Of Bio-matrix Graduate School Tokyo Medi
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Sato Daisuke
Oral Implantology And Regenerative Dental Medicine Department Of Masticatory Function Rehabilitation
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Kasugai S
Section Of Oral Implantology And Regenerative Dental Medicine Department Of Masticatory Function Reh
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KURODA Shinji
Oral Implantology and Regenerative Dental Medicine, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
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