Cadmium Induces Expression of Metallothionein in Rat Dental Pulp
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概要
- 論文の詳細を見る
Metallothionein(MT)is a metalloprotein with high affinity for certain heavy metals.In the present study, the ability of cadmium(Cd)to induce the synthesis of MT in dental pulp was investigated.Rats were injected subcutaneously with CdCl2(1.5 mg Cd/kg)daily for 7 days.Expression of the MT gene was demonstrated by reverse transcription polymerase chain−reaction techniques.The results indicate that Cd induced MT in dental pulp of rat incisor and this may be involved in the cellular defense mechanism against Cd toxicity.
- 社団法人 日本薬理学会の論文
- 2000-08-01
著者
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Ohya Keiichi
Pharmacology Department Of Hard Tissue Engineering Graduate School Tokyo Medical And Dental Universi
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Ohya Keiichi
Pharmacology Department Of Hard Tissue Engineering Division Of Bio-matrix Graduate School Tokyo Medi
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Ohya Keiichi
Section Of Pharmacology Dep. Of Hard Tissue Engineering Div. Of Bio-matrix Graduate School Tokyo Med
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TAMURA Yukihiko
Pharmacology, Department of Hard Tissue Engineering, Division of Bio-Matrix, Graduate School, Tokyo
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Tamura Yukihiko
Section Of Pharmacology Dep. Of Hard Tissue Engineering Div. Of Bio-matrix Graduate School Tokyo Med
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Tamura Yukihiko
Pharmacology Dept. Of Hard Tissue Engineering Division Of Bio-matrix Graduate School Tokyo Medical A
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Ohya Kenichi
Pharmacology, Department of Hard Tissue Engineering, Division of Bio-Matrix, Graduate School, Tokyo Medical and Dental University
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