719 フッ素コーティングの選択的親水化による細胞接着制御技術の開発(S07-3 マイクロ・ナノバイオメカニクス(3),S07 マイクロ・ナノバイオメカニクス)

概要

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Cell adhesion plays a crucial role to maintain a cell shape and a tissue structure. Therefore, in tissue engineering, cell adhesion control is an essential factor to induce artificial tissue reorganization. Then in cell biomechanics, innovation of observation technique has brought a high spatial and temporal resolution. This innovation of observation object also requires accurate cell adhesion control to maintain cell position and cell shape. In this study, we proposed a novel surface modification process to make a micro cell adhesion pattern. Fluorine polymer was coated onto a cover glass, and micro hydrophilized pattern was fabricated by using a stencil mask and exposure to O_2 ion flux or O_2 plasma. To evaluate an effect of hydrophilization treatment, modified surface of cover glass was observed using optical microscope, and a contact angle of water on the modified surface was measured.
一般社団法人日本機械学会の論文
2006-09-15