3304 自動採血用チタン合金マイクロ針創製と機能評価(S26-1 生体・環境適合材料の創製・強度評価技術開発1,S26 生体・環境適合材料の創製・強度評価技術開発)

概要

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The purpose of this study is to generate and characterize a titanium alloy microneedle, which can be equipped in Bio-MEM such as HMS (Health Monitoring System) for the blood sugar level measurement. One of the most important subject for the Bio-MEM is a microneedle with a inner diameter of 100μm and a outer one of 200μm, which mimics female mosquito's painless blood extraction mechanism. In this study, a microneedle generation was performed through 1) selection of a biocompahble material from titanium alloys by the cytotoxic assay, 2) RF magnetron sputter generating of the microtubes with a inner diameter of 100μm, a outer one of 200μm and a length of 4mm, and 3) evaluation of suction by the vacuum blood extraction tests. Consequently, the titanium microneedle obtained the flow rate of 6.2μl/sec.
2006-09-15