Determinants of Heart Rate Recovery in Patients with Suspected Coronary Artery Disease
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概要
- 論文の詳細を見る
Background: Heart rate recovery after exercise is an independent prognosticindicator for cardiovascular and all-cause mortality. The purpose of this study was toclarify the clinical determinants of heart rate recovery.Methods and results: We examined 114 consecutive male patients who underwentexercise myocardial perfusion single-photon emission computed tomography andechocardiography for the evaluation of suspected coronary artery disease. Heart raterecovery was obtained from the subtraction of heart rate in the first minute of recoveryafter exercise from maximal heart rate during exercise. Abnormal heart rate recoverywas present in 50 patients (43.9%). Patients with abnormal heat rate recovery weremore likely to have diabetes mellitus.Patients with abnormal heart rate recovery had a higher heart rate at rest thanthose with normal heart rate recovery (77.5 ± 13.6 vs. 72.3 ± 12.5 (bpm), p<0.05).However, no differences in left ventricular geometry investigated withechocardiography were observed between patients with normal and abnormal heartrate recovery. Furthermore, there was no difference in various scintigraphic variablesbetween patients with normal and abnormal heart rate recovery. A stepwisemultivariate analysis showed that heart rate at rest and diabetes mellitus wereindependent predictor of heart rate recovery (p<0.05).Conclusion: Our results suggested that heart rate recovery is associated withclinical factors related to the cardiac autonomic function such as diabetes mellitus andheart rate at rest, but not with other ones such as left ventricular geometry andmyocardial ischemia.
- 神戸大学の論文
著者
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Yokoyama Mitsuhiro
Department Of Cardiovascular Medicine Awaji Prefectural Hospital
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Yokoyama Mitsuhiro
Department Of Cardiology Kobe University Graduate School Of Medicine
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Hideyuki Shiotani
Faculty Of Health Sciences Kobe University School Of Medicine
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Yokoyama Mitsuhiro
Department Of Internal Medicine Kobe University Graduate School Of Medicine
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Nonaka Akiko
Department Of Cardiovascular And Respiratory Medicine Hyogo Cancer Center
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Kitano Kimiko
Faculty of Health Sciences, Kobe University School of Medicine
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Kitano Kimiko
Faculty Of Health Science Kobe University School Of Medicine
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Kitano Kimiko
Faculty Of Health Sciences Kobe University School Of Medicine
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