冠動脈硬化症に対するLDLアフェレシス治療(<特集>動脈硬化とアフェレシス)

概要

論文の詳細を見る
The efficacy and safety of the therapeutic tool which directly removes LDL particles from circulation (LDL apheresis) have already been established for cholesterol-lowering in patients with refractory hypercholesterolemia. Several angiographic studies have demonstrated that regular LDL apheresis therapy had favorable effects on the progression of coronary atherosclerosis. In addtion, two clinical reports described excellent long-term follow-up results for patients with coronary artery disease who had been treated with LDL apheresis using dextran sulfate cellulose columns plus adjunctive cholesterol-lowering drug therapy. Since the mechanisms of clinical improvement caused by LDL apheresis extend beyond simple and drastic reduction of LDL cholesterol, further investigation based on recent vascular biological evidence is needed.
日本アフェレシス学会の論文
2008-02-29