Chlorination Byproducts of Epoxy Resin Hardener and Mutagenic Assay of Their Products
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概要
- 論文の詳細を見る
The reaction of 4, 4'-methylenedianiline (MDA) with chlorine in aqueous solution was investigated by gas chromatography/mass spectrometry (GC/MS) in order to determine its chemical changes in water. MDA was shown to react readily with chlorine under conditions likely to be found during water treatment disinfection. The reaction of MDA with chlorine in water was dependent on the solution pH and the molar ratios of chlorine to MDA. The disinfection products of p-benzoquinone, p-chloroaniline, 2, 4-dichloroaniline, 2, 4, 6-trichloroaniline, and p-aminophenol were identified and them of p-aminobenzyl chloride, p-aminobenzaldehyde and p-methoxyaniline were estimated in the chlorination MDA solution. The mutagenic activity of the chlorination byproducts extracted from the chlorination MDA solution was evaluated using umu-test.
- 公益社団法人日本薬学会の論文
- 2008-02-01
著者
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Onodera Sukeo
Faculty Of Pharmaceutical Science Science University Of Tokyo
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Yaguchi Kumiko
Tokyo Metropolitan Research Laboratory Of Public Health
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Tomiyama Satoshi
Faculty of Pharmaceutical Sciences, Tokyo University of Science
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Takahashi Yasuo
Tokyo Metropolitan Research Laboratory of Public Health
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Tomiyama Satoshi
Faculty Of Pharmaceutical Sciences Tokyo University Of Science
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