犬の傅染性圓形細胞肉腫の移植試驗

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The author deals with an experimental study of the infectious round-cell sarcoma of dogs in this report. He found a sarcoma on the prepuce of penis of a "Kai" dog and transplanted it successfully to the subcutaneous tissue under peritoneum of 5 infantile mongrels aged less than 1 year. The results of the experiment are as follows : 1. This sarcoma was transplanted easily to other dogs with some emulsion of the tissue prepared by adding some Ringer's solution. 2. Such transplantation was repeated for three generations and no remarkable changes in the macroscopic as well as microscopic characteristics were found in the succesive generations of the sarcoma. 3. The growth of the sarcoma is expansive, but the haematic and lymphatic metastases are also possible, especially in infantile dogs. 4. The infantile dogs infected with the sarcoma offen died from the cachexia of the sarcoma itself. 5. The sarcoma occasionally moved to the lungs, kidneys, small intestines and lymphatic glands. 6. This sarcoma was identified as the infectious round cell-sarcoma by its histological and biological characteristics. 7. The pathogene appears to remain in the body of the infected dog for comparatively a long time, being considered from the possibilities of transmission, transplantation, metastasis, and recurrence of the sarcoma.
帯広畜産大学の論文
1951-03-25