Synthesis and Cytotoxicity of Indolopyrrolemaleimides
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概要
- 論文の詳細を見る
A series of indolopyrrolemaleimides have been synthesized and evaluated for their cytotoxicity in vitro against human leukemia cell line and four human solid cancer cell lines. Some of the compounds showed high or mediate activity against the lines. 6dc is the most promising compound among them. The inhibition toward topoisomerase I was also studied.
- 公益社団法人日本薬学会の論文
- 2007-09-01
著者
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YANG Bo
Department of Cardiology, Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese
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He Qiao-jun
Department Of Pharmacology School Of Pharmaceutical Sciences Zhejiang University
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Yang Bo
Department Of Cardiology Key Laboratory Of Cardiovascular Remodeling And Function Research Chinese M
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Hu Yong-zhou
Zju-ens Joint Laboratory Of Medicinal Chemistry School Of Pharmaceutical Sciences Zhejiang Universit
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Zhang Chong
Department of Chemical Engineering, Tsinghua University
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Yang Bo
Department Of Pharmacology School Of Pharmaceutical Sciences Zhejiang University
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Guo Peng
Zju-ens Joint Laboratory Of Medicinal Chemistry School Of Pharmaceutical Sciences Zhejiang Universit
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Zhang Chong
Department Of Chemical Engineering Tsinghua University
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Zhang Chong
Department Of Pharmacology School Of Pharmaceutical Sciences Zhejiang University
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Xu Gui-qing
Zju-ens Joint Laboratory Of Medicinal Chemistry School Of Pharmaceutical Sciences Zhejiang Universit
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