Sedative Effect of Centranthus longiflorus ssp. longiflorus in Rats and the Influence of Adrenalectomy on its Effect

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概要

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• Sedative effect of the aqueous extract of Centranthus longiflorus ssp. longiflorus (Cle-1) on intact and adrenalectomized rats was investigated using a thiopental sleeping test to clarify the relationship of this effect on adrenal gland hormones, particularly glucocorticoids. Adrenal gland hormones were found to play an important role in inhibiting the sedative effect of the investigated drugs. It is clear, however, that these hormones are not glucocorticoids. Glucocorticoids were not responsible for shortening the sleep period.

• 公益社団法人日本薬学会の論文
• 2007-08-01

著者

• Suleyman Halis

  Department Of Pharmacology Faculty Of Medicine Ataturk University

• Guvenalp Zuhal

  Department Of Pharmacognosy Faculty Of Pharmacy Ataturk University

• Halis Halis

  Department of Pharmacology, Faculty of Medicine, Ataturk University

• KIZILKAYA Mehmet

  Department of Anesthesiology, Faculty of Medicine, Ataturk University

• DEMIREZER L.

  Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University

• Kizilkaya Mehmet

  Department Of Anesthesiology Faculty Of Medicine Ataturk University

• Demirezer L.

  Department Of Pharmacognosy Faculty Of Pharmacy Hacettepe University

• Halis Halis

  Department Of Pharmacology Faculty Of Medicine Ataturk University

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