SYNTHESIS OF BREDININ 5'-ALKYLPHOSPHATES INVOLVING PHOTOCHEMICAL MANIPULATION OF THE IMIDAZOLE MOIETY, AND THEIR ANTITUMOR ACTIVITIES(Communications to the Editor)

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概要

• 論文の詳細を見る

• Bredinin 5'-oleyl and 5'-cetyl phosphates (2a and 2b), prepared from 1-β-D-ribofuranosyl-5-aminoimidazole-4-carboxamide via a photochemical ring-opening reaction of the imidazole moiety, showed remarkable antitumor effects against various transplantable mouse tumors, and were clearly superior to bredinin (1).

• 公益社団法人日本薬学会の論文
• 1987-08-25

著者

• Shuto Satoshi

  Research Laboratories Toyo Jozo Co. Ltd

• UEDA TOHRU

  Faculty of Pharmaceutical Sciences, Hokkaido University

• Itoh H

  Research Laboratories Toyo Jozo Co. Ltd

• Ueda T

  Nagoya City Univ. Nagoya Jpn

• Itoh Hiromichi

  Research Laboratories, Toyo Jozo Co., Ltd

• Endo Eriko

  Research Laboratories, Toyo Jozo Co., Ltd

• Fukukawa Kiyofumi

  Research Laboratories, Toyo Jozo Co., Ltd

• Tsujino Masatoshi

  Research Laboratories, Toyo Jozo Co., Ltd

• Endo E

  Research Laboratories Toyo Jozo Co. Ltd

• Fukukawa Kiyofumi

  Research Laboratories Toyo Jozo Co. Ltd

• Tsujino M

  Toyo Jozo Co. Ltd. Shizuoka Jpn

• Ueda Tohru

  Faculty Of Bioresource Sciences Akita Prefectural University

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• SYNTHESIS OF BREDININ 5'-ALKYLPHOSPHATES INVOLVING PHOTOCHEMICAL MANIPULATION OF THE IMIDAZOLE MOIETY, AND THEIR ANTITUMOR ACTIVITIES(Communications to the Editor)
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