Influence of Hypothyroidism Induced by Thiamazole on the Toxicity of Fluconazole in Chick Embryos
スポンサーリンク
概要
- 論文の詳細を見る
The effect of hypothyroidism induced by thiamazole on the toxicity of fluconazole was studied in chick embryos. To our knowledge, no information is now available on the effects of thyroid gland function on the regeneration and differentiation of tissue. Fertilized eggs of White Leghorns were incubated and investigated. 1.2 mg/0.2 mL/egg of thiamazole was injected into the albumen of fertilized eggs on the 9^<th> day of incubation. Fluconazole at 0.4 mg/egg was injected into the air sac of fertilized eggs on the 16th day of incubation. Electrocardiograms were recorded 0 to 60 min after the injection. After the injection of fluconazole into the thiamazole-treated eggs, the heart rate was significantly decreased compared with the untreated eggs. These findings indicate that hypothyroidism induced by thiamazole has a marked influence on the toxicity of fluconazole in chick embryos.
- 日本再生歯科医学会の論文
- 2006-09-30
著者
-
YAGO Kazuo
Department of Pharmacy, Kitasato University Hospital
-
YOSHIYAMA Yuji
Division of Clinical Pharmacy, Kyoritsu University of Pharmacy
-
KANKE Motoko
Division of Clinical Pharmacy, Kyoritsu University of Pharmacy
-
Yago Kazuo
Department Of Hospital Pharmacy Kitasato University East Hospital
-
Kanke Motoko
Division Of Clinical Pharmacy Kyoritsu University Of Pharmacy
-
Yoshiyama Yuji
Division Of Clinical Pharmacy Kyoritsu University Of Pharmacy
-
OTORI Katsuya
Department of Pharmacy, Kitasato University Hospital
-
Otori Katsuya
Department Of Pharmacy Kitasato University Hospital
関連論文
- Benzyl Derivatives of N-2,4-Dinitrophenyl-D-glucosamine and Their Use for Oligosaccharide Synthesis
- Syntheses of Penta-O-benzyl-myo-inositols, O-β-L-Arabinosyl-(1→2)-sn-myo-inositol, O-α-D-Galactosyl-(1→3)-sn-myo-inositol, and O-α-D-Galactosyl-(1→6)-O-α-D-Galactosyl-(1→3)-sn-myo-inositol
- Glycosylation Using 2-Azido-3,4,6-tri-ο-benzyl-2-deoxy-D-glucose,-galactose, and -mannose with the Aid of ρ-Nitrobenzenesulfonyl Chloride-Silver Trifluoromethanesulfonate-Triethylamine System
- Synthesis of Glucose-Containing Linear Oligosaccharides Having α(1→4) and α(1→6) Linkages Using Stereoselective Dehydrative Glycosylation
- The effect of fosfomycin on nedaplatin-induced nephrotoxicity in rats
- Protective Effect of Fleroxacin against the Nephrotoxicity of Isepamicin in Rats
- The effect of fosfomycin on glycopeptide antibiotic-induced nephrotoxicity in rats
- Experimental Diabetes Model in Chick Embryos Treated with Streptozotocin(Pharmacology)
- Influence of the Light Schedule on the Toxicity of Amitriptyline in Chick Embryos(Pharmacology)
- Toxic Interactions between Amitriptyline and Disopyramide in Chick Embryos
- Drug-Drug Interactions between Antiarrhythmic Drugs in Chick Embryos(Pharmacology)
- Cardiotoxicity of Trastuzumab (Herceptin) in Chick Embryos
- Toxic Effects of Trastuzumab (Herceptin) Combined with Doxorubicin in Chick Embryos
- Influence of the Light Schedule on the Toxic Interaction between Propranolol and Disopyramide in Chick Embryos
- Toxic Interactions between Disopyramide and Propranolol in Chick Embryos
- Pharmacokinetics and Variation in the Clearance of Oxycodone and Hydrocotarnine in Patients with Cancer Pain(Miscellaneous)
- Relationship between Serum Fentanyl Concentration and Transdermal Fentanyl Dosage, and Intra-individual Variability in Fentanyl Concentration after Application of Fentanyl Patches in Patients with Cancer Pain
- Determination of Oxycodone and Hydrocotarnine in Cancer Patient Serum by High-Performance Liquid Chromatography with Electrochemical Detection
- Cardiotoxicity of Anticancer Drug in Chick Embryos
- Toxic Interactions between Miconazole and Disopyramide in Chick Embryos
- Toxic Interactions Between Amitriptyline and Fluconazole in Chick Embryos
- Influence of Hypothyroidism Induced by Thiamazole on the Toxic Interaction between Propranolol and Disopyramide in Chick Embryos(Pharmacology)
- Influence of Hypothyroidism Induced by Thiamazole on the Toxicity of Fluconazole in Chick Embryos
- Influence of hypothyrodism induced by thiamazole on the drug interaction in chick embryos
- Influence of Hypothyroidism Induced by Thiamazole on the Toxicity of Amitriptyline in Chick Embryos(Pharmacology)
- Evaluation of the Effective Drugs for the Prevention of Nausea and Vomiting Induced by Morphine Used for Postoperative Pain : A Quantitative Systematic Review
- Liver abscess that responded well to pazufloxacin therapy
- Stereoselective Syntheses of α-Glucuronides Using Dehydrative Glycosylation
- Toxic Interactions between Fluconazole and Disopyramide in Chick Embryos(Pharmacology)
- NEPHROTOXICITY OF TEICOPLANIN IN RATS
- Protective Effect of Ceftriaxone against the Nephrotoxicity of Isepamicin Administered Once Daily in Rats
- Effect of Digoxin on Chick Embryos with Hyperthyroidism Induced by L-Thyroxin
- Clinical efficacy of arbekacin for Gram-negative bacteria
- Investigation and threshold of optimum blood concentration of voriconazole : a descriptive statistical meta-analysis
- Survey on the Attitudes of Pharmacy Students in Japan toward Doping and Supplement Intake
- .ALPHA.-D-glucosylation by 6-O-acetyl-2,3,4-tri-O-benzyl-D-glucopyranose using trimethylsilyl triflate and pyridine. Synthesis of .ALPHA.-maltosyl and .ALPHA.-isomaltosyl .ALPHA.-D-glucosides.
- History and Social Duties in Future of the AATEX: Alternatives to Animal Testing and Experimentation